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Youth at risk of homelessness in Indianapolis have new transitional housing options through the expansion of a local program.

Eli Lilly's diabetes treatment Mounjaro, which is widely used for weight loss, raked in nearly $1 billion in second-quarter sales, or more than $200 million above what Wall Street had expected.

A new retail incubator pilot program in Indianapolis announced its first business to set up shop in the historic Stutz building.

Members of the Fayette County Board of Education voted unanimously Monday night to bring district policy in line with new state restrictions that limit classroom speech about gender and sexuality and bathroom access for transgender students.

The southwest quadrant of Monument Circle will close to vehicle traffic as Spark on the Circle takes over.

Disgraced sports doctor Larry Nassar has been stabbed multiple times during an altercation with another inmate at a federal prison in Florida. Nassar is serving decades in prison after admitting sexually assaulting athletes at Michigan State University and at Indianapolis-based USA Gymnastics, including Olympic medalists.

Indianapolis police said a suspect detained at the Indianapolis Adult Detention Center assaulted a sheriff’s deputy and stole a van, crashing it outside the Community Justice Campus.

Since he began performing as a teenager, Miles Mason has been known on the stage as Dead Silence. "Vanilla Bean" is his new single that's now available. But just a few months ago, Miles' career and his life were almost silenced by a fire at his apartment complex on the northwest side of Indianapolis. He is still recovering from his injuries, and he stopped by WFYI for a conversation with local Morning Edition host Ray Steele.

The sheriff’s deputy who died after he was attacked by a detainee at the Indianapolis Adult Detention Center Monday was strangled with handcuffs, according to court documents.

The Marion County Prosecutor’s Office announced Thursday it will seek the death penalty for a man charged in the killing of Marion County Sheriff’s Deputy John Durm this week.