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A change from pre-pandemic, the assessment of homelessness in Indianapolis will once again be taken over a period of days but still represent a single night in January.

Indianapolis saw another record-breaking year for homicides, with 271 people killed.

New research finds a strong association between a rare genetic mutation and early-onset heart failure and hospitalization among Black Americans. Patients of African descent carrying this genetic mutation developed heart failure four years earlier than those not carrying it.

The College Football Playoff National Championship game will be played in Indianapolis on Jan. 10. The city has been looking forward to hosting the game since it was announced in 2017.

A hiring event will take place Thursday to fill numerous positions at Indianapolis Animal Care Services.

A 16-year-old Indianapolis boy faces murder, robbery and other charges in connection with the shooting deaths of three people on the city's south side, prosecutors said.

The Indianapolis City-County Council held its last full meeting of 2021 Monday night.

The NCAA has made revisions to its constitution, which is getting pared down. Passing a revised constitution at the NCAA convention in January is the first step in a two-phase process that will allow each division of the association to govern itself.

IndyGo board of directors is set to vote on the approval of construction contracts for the Purple Line Thursday.

A homeless shelter on Indianapolis' east side is currently providing services to a record number of people.