Plans to vaccinate Americans against COVID-19 had a setback Tuesday. Federal officials called for a pause on Johnson & Johnson's vaccine, to look into reports that it causes blood clots. And that news reverberated at clinics where the vaccine had already been used.

Appointments are now available at the Marion County Public Health Department's new COVID-19 vaccine clinic on the eastside, located at 9503 E. 33rd St.

The Indiana Department of Health announced Tuesday it is pausing use of the Johnson & Johnson vaccine after national guidance to do so. The state is working to supply vaccination sites with other vaccines.

Despite more than 1.4 million Hoosiers fully vaccinated, the state is seeing an increase in cases and hospitalizations. That's because the state is in a race against more infectious variants.

The University of Notre Dame will require all students to get a COVID-19 vaccine before returning for the fall 2021 semester.

States across the Midwest are opening up COVID-19 vaccine appointments to more age groups. This should move the region closer to herd immunity and the return to some normalcy. Still, some say they don't want to get vaccinated.

A total of 1,291,190 Hoosiers -- 23.7 percent of Indiana's residents who are at least 16 -- have been fully vaccinated, while 1,827,696 first doses of vaccine have been administered statewide.

After the NCAA tournament, the emphasis turns to how the city will move forward in COVID-19 mitigation and vaccination efforts.

The funding from the Centers for Disease Control and Prevention will help programs such as door-to-door outreach to raise awareness about vaccinations or help people sign up to get vaccinated.

The Midwest is home to tens of thousands of immigrants -- including refugees from countries like Myanmar, the Democratic Republic of the Congo and Iraq. And it's been a challenge to provide information about COVID-19 and vaccines to those who don't speak English.