The case is not the first time a coronavirus-related issue has been before the court, but it is the first time it has been asked to weigh in on a vaccine mandate.

Ball State University President Geoffrey Mearns announced in a message to faculty that masks would be required in all university buildings beginning Monday. And Valparaiso University is requiring all students, faculty and staff to receive the COVID-19 vaccine before the start of the fall semester.

The COVID-19 delta variant accounts for more than 80 percent of sampled positive cases in Indiana. State health officials have pointed to the variant as the main driver of Indiana’s recent climb in new cases and hospitalizations.

A federal appeals court ruled Monday that Indiana University can proceed with its plan to require students and employees to get vaccinated for COVID-19.

The new guidance is targeted at vaccinated people who live in areas with "high and substantial transmission" and focuses on indoor settings.

An eastside Indianapolis church with nearly 11,000 members has been busy during the pandemic to maintain accessibility to their worshippers.

A new school year starts for many Hoosier students in the next two weeks, as COVID-19 cases are on the rise.

Vaccination rates for Purdue students are about twice the rate compared with individuals ages 16-29 across the state, the school said.

A ruling from a judge in South Bend has rejected a request from eight IU students who sought to block the COVID-19 vaccine requirement.

Washington, Indianapolis, Arizona and the Los Angeles Chargers had the four lowest COVID-19 vaccination rates in the league as of Thursday, according to the source familiar with the vaccination rates.