Plans to vaccinate Americans against COVID-19 had a setback Tuesday. Federal officials called for a pause on Johnson & Johnson's vaccine, to look into reports that it causes blood clots. And that news reverberated at clinics where the vaccine had already been used.

Despite more than 1.4 million Hoosiers fully vaccinated, the state is seeing an increase in cases and hospitalizations. That's because the state is in a race against more infectious variants.

The Indiana Department of Health announced Tuesday it is pausing use of the Johnson & Johnson vaccine after national guidance to do so. The state is working to supply vaccination sites with other vaccines.

States across the Midwest are opening up COVID-19 vaccine appointments to more age groups. This should move the region closer to herd immunity and the return to some normalcy. Still, some say they don't want to get vaccinated.

The University of Notre Dame will require all students to get a COVID-19 vaccine before returning for the fall 2021 semester.

A total of 1,291,190 Hoosiers -- 23.7 percent of Indiana's residents who are at least 16 -- have been fully vaccinated, while 1,827,696 first doses of vaccine have been administered statewide.

After the NCAA tournament, the emphasis turns to how the city will move forward in COVID-19 mitigation and vaccination efforts.

The funding from the Centers for Disease Control and Prevention will help programs such as door-to-door outreach to raise awareness about vaccinations or help people sign up to get vaccinated.

The Midwest is home to tens of thousands of immigrants -- including refugees from countries like Myanmar, the Democratic Republic of the Congo and Iraq. And it's been a challenge to provide information about COVID-19 and vaccines to those who don't speak English.

Some school leaders are allowing employees to decide, and have organized clinics to provide them with the opportunity to get vaccinated or offered incentives for those who do.