Philip Rivers knows he may have made the last start of his improbable comeback. Rivers ended a five-year retirement to rejoin the quarterback-needy Indianapolis Colts at age 44. But he couldn't stop the Colts' losing streak.

Jim Irsay, the Indianapolis Colts’ owner who leveraged the popularity of Peyton Manning into a new stadium and a Super Bowl title, died Wednesday at age 65.

Indianapolis hosts its 38th consecutive NFL Scouting Combine this weekend. Interested fans can watch for free or participate in the NFL Combine Experience in the parking lot of Lucas Oil Stadium.

The Indianapolis Colts are trying to halt the NFL's longest winless streak in season openers. The Colts haven't won any of their last 10 openers. That streak includes one tie, in 2022.

From the owner’s suite to the front office to the sideline, the number of women in the NFL is steadily rising. And, they’re here to stay.

The program will invite medical students from historically Black colleges and universities to do clinical rotations with NFL teams.

The program in honor of the Pro Football Hall of Fame coach, announced Monday by the Irsay family that owns the Colts, will provide the team with access to talented coaches while fostering and expanding the team’s diversity, equity and inclusion initiatives.

The Indianapolis police officer who shot and killed Dreasjon Reed last year is suing the National Football League over social media posts that associate Reed with other victims of officer-involved killings.

Joining Manning as a finalist was one of the players he threw to, wide receiver Reggie Wayne, a finalist for the second time.

Teams can conduct classroom instruction and on-field activities through Zoom meetings or similar apps instead of at their facilities, and players can voluntarily wear monitors to track workouts.