The Indiana Department of Health added 15,277 new confirmed COVID-19 cases to the state's total, pushing it beyond 1.3 million confirmed for the entire pandemic.

Indiana House Republicans' 2022 agenda is led by efforts to cut $1 billion in taxes and curb COVID-19 vaccine mandates.

A bill to effectively ban private companies from enforcing COVID-19 vaccine mandates cleared its first hurdle at the Statehouse Thursday.

The Indiana Department of Health announced late Wednesday Hoosiers 12 to 15 years old are now eligible for booster shots.

State Health Commissioner Dr. Kris Box has become reinfected with COVID-19. She tested positive after developing symptoms on Monday, and has been isolating at home.

The Republican-dominated state Legislature started its 2022 session Tuesday and planned to quickly take up actions that GOP Gov. Eric Holcomb says will allow him to drop the emergency declaration that he first issued in March 2020.

The University of Notre Dame has reinstated a mask requirement for all students, staff and campus visitors as the omicron variant fuels a surge in COVID-19 cases across the country.

Indiana experienced COVID-19 whiplash throughout 2021 – setting both pandemic lows and record highs for cases and hospital capacity. But what did 2021 look like in Indiana by the numbers?

Purdue University Tuesday outlined its plans for an in-person start to the second semester, as the school reported its sharpest increase in COVID-19 testing positivity rates this academic year.

The Indiana Department of Health will limit rapid antigen COVID-19 testing at state sites to Hoosiers 18 and younger and symptomatic Hoosiers 50 and older.