All of Indiana's more than 600 political subdivisions have agreed to take part in a $507 million statewide settlement with opioid makers and distributors, Indiana's attorney general's office said.

The Centers for Disease Control and Prevention released its provisional report on overdose deaths in 2021 across the United States. In Indiana, the number hit a record high for a second year in a row.

Indiana is set to receive more than $500 million over the next two decades from a settlement with opioid manufacturers.

Overdose Lifeline, Inc., an Indiana nonprofit that helps those affected by substance use disorder, will distribute 35,000 doses of naloxone.

The funds will provide participants with training in jobs that address the impact of the opioid crisis, including recovery coaches, peer navigators and community health workers.

Indiana will receive $507 million as part of a multi-state agreement to settle a lawsuit against opioid distributors designed to bring relief to people struggling with addiction to the drug, officials said Wednesday.

A state law signed by Gov. Eric Holcomb this year requires cities and counties that want to pursue their own legal action to "opt out" of the attorney general's lawsuits by June 30.

West Lafayette and Lafayette are among an estimated 50 local governments in the state pursuing lawsuits against manufacturers and distributors of prescription opioids for damages caused by the opioid crisis.

The settlement with New York-based McKinsey & Company is the first multistate opioid settlement to result in a substantial payout to states.

Indiana is getting more people with mental health and substance use disorders connected with peer supports trained professionals who have personal experience with those challenges.